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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSIN_2000Mevalonate kinase. (276 aa)    
Predicted Functional Partners:
SSIN_1999
Diphosphomevalonate decarboxylase.
 
 
 0.992
SSIN_1998
Phosphomevalonate kinase.
 
 
 0.989
fni
Isopentenyl-diphosphate delta-isomerase, FMN-dependent; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.976
SSIN_1996
Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 0.973
SSIN_1995
Hydroxymethylglutaryl-CoA synthase.
 
 
 0.905
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
    
 0.570
SSIN_2001
Beta-lactamase, class C.
       0.516
SSIN_2002
C3-degrading proteinase.
       0.515
SSIN_1035
Threonine synthase.
    
  0.454
SSIN_1548
Trans-2,cis-3-Decenoyl-ACP isomerase.
   
 
  0.428
Your Current Organism:
Streptococcus sinensis
NCBI taxonomy Id: 176090
Other names: CCUG 48363, CCUG 48488, DSM 14990, LMG 21517, LMG:21517, S. sinensis, Streptococcus sinensis Woo et al. 2002, strain HKU4
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