Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSIN_2017Membrane-associated zinc metalloprotease. (418 aa)    
Predicted Functional Partners:
SSIN_2018
Phosphatidate cytidylyltransferase; Belongs to the CDS family.
  
  
 0.827
SSIN_2019
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
  
 0.810
proS
Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
  
    0.792
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
   
  
 0.694
SSIN_1057
Transcriptional regulator.
      
 0.687
SSIN_0051
Octaprenyl-diphosphate synthase; Dimethylallyltransferase; Geranyltranstransferase (farnesyldiphosphate synthase); Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
 
    0.582
SSIN_1239
Positive transcriptional regulator, MutR family.
      
 0.562
SSIN_1287
Signal peptidase I; Belongs to the peptidase S26 family.
 
  
 0.561
SSIN_2020
Preprotein translocase subunit YajC; TCDB 3.A.5.1.1.
     
 0.541
SSIN_1423
ABC transporter, permease protein EscB.
  
   
 0.539
Your Current Organism:
Streptococcus sinensis
NCBI taxonomy Id: 176090
Other names: CCUG 48363, CCUG 48488, DSM 14990, LMG 21517, LMG:21517, S. sinensis, Streptococcus sinensis Woo et al. 2002, strain HKU4
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