STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAMN02949497_0711Menaquinone-dependent protoporphyrinogen oxidase. (181 aa)    
Predicted Functional Partners:
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
 0.738
hemF
Oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
     
 0.732
SAMN02949497_4574
Coproporphyrinogen-III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.718
SAMN02949497_4584
Heme chaperone HemW; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.697
SAMN02949497_0712
LysM domain-containing protein.
       0.581
SAMN02949497_0877
CRP/FNR family transcriptional regulator, cyclic AMP receptor protein.
  
     0.432
SAMN02949497_4581
Uroporphyrin-3 C-methyltransferase.
  
  
 0.425
SAMN02949497_0713
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
       0.422
SAMN02949497_0279
Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
    
  0.416
SAMN02949497_3023
Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
    
  0.416
Your Current Organism:
Methylomagnum ishizawai
NCBI taxonomy Id: 1760988
Other names: DSM 29768, JCM 18894, KCTC 4681, M. ishizawai, Methylocaldum sp. 175, Methylomagnum ishizawai Khalifa et al. 2015 emend. Frindte et al. 2017, NBRC 109438, strain RS11D-Pr
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