node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFT75158.1 | SFT99564.1 | SAMN04487915_10335 | SAMN04487915_10774 | Protein of unknown function. | Proteasome accessory factor A. | 0.666 |
SFT75158.1 | arc | SAMN04487915_10335 | SAMN04487915_10775 | Protein of unknown function. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.798 |
SFT75158.1 | pafA | SAMN04487915_10335 | SAMN04487915_10770 | Protein of unknown function. | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.735 |
SFT75158.1 | prcA | SAMN04487915_10335 | SAMN04487915_10771 | Protein of unknown function. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.985 |
SFT75158.1 | prcB | SAMN04487915_10335 | SAMN04487915_10772 | Protein of unknown function. | Proteasome endopeptidase complex, beta component Threonine peptidase. MEROPS family T01B; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.964 |
SFT99468.1 | SFT99498.1 | SAMN04487915_10767 | SAMN04487915_10769 | Transcriptional regulator. | Peptidylprolyl isomerase. | 0.579 |
SFT99468.1 | SFT99564.1 | SAMN04487915_10767 | SAMN04487915_10774 | Transcriptional regulator. | Proteasome accessory factor A. | 0.475 |
SFT99468.1 | arc | SAMN04487915_10767 | SAMN04487915_10775 | Transcriptional regulator. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.620 |
SFT99468.1 | pafA | SAMN04487915_10767 | SAMN04487915_10770 | Transcriptional regulator. | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.781 |
SFT99468.1 | prcA | SAMN04487915_10767 | SAMN04487915_10771 | Transcriptional regulator. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.718 |
SFT99468.1 | prcB | SAMN04487915_10767 | SAMN04487915_10772 | Transcriptional regulator. | Proteasome endopeptidase complex, beta component Threonine peptidase. MEROPS family T01B; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.535 |
SFT99498.1 | SFT99468.1 | SAMN04487915_10769 | SAMN04487915_10767 | Peptidylprolyl isomerase. | Transcriptional regulator. | 0.579 |
SFT99498.1 | SFT99564.1 | SAMN04487915_10769 | SAMN04487915_10774 | Peptidylprolyl isomerase. | Proteasome accessory factor A. | 0.561 |
SFT99498.1 | SFT99588.1 | SAMN04487915_10769 | SAMN04487915_10776 | Peptidylprolyl isomerase. | tRNA (adenine-58-N(1)-) methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. | 0.583 |
SFT99498.1 | arc | SAMN04487915_10769 | SAMN04487915_10775 | Peptidylprolyl isomerase. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.470 |
SFT99498.1 | pafA | SAMN04487915_10769 | SAMN04487915_10770 | Peptidylprolyl isomerase. | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.699 |
SFT99498.1 | prcA | SAMN04487915_10769 | SAMN04487915_10771 | Peptidylprolyl isomerase. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.728 |
SFT99498.1 | prcB | SAMN04487915_10769 | SAMN04487915_10772 | Peptidylprolyl isomerase. | Proteasome endopeptidase complex, beta component Threonine peptidase. MEROPS family T01B; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.728 |
SFT99498.1 | pup | SAMN04487915_10769 | SAMN04487915_10773 | Peptidylprolyl isomerase. | Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. | 0.617 |
SFT99564.1 | SFT75158.1 | SAMN04487915_10774 | SAMN04487915_10335 | Proteasome accessory factor A. | Protein of unknown function. | 0.666 |