node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDK42560.1 | pdxJ | SAMN04487898_108137 | SAMN04487898_111103 | NADH-FMN oxidoreductase RutF, flavin reductase (DIM6/NTAB) family. | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.571 |
SDK74230.1 | SDK74266.1 | SAMN04487898_111104 | SAMN04487898_111105 | Mechanosensitive ion channel. | Hypothetical protein. | 0.786 |
SDK74230.1 | gcvP | SAMN04487898_111104 | SAMN04487898_111102 | Mechanosensitive ion channel. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.467 |
SDK74230.1 | pdxJ | SAMN04487898_111104 | SAMN04487898_111103 | Mechanosensitive ion channel. | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.622 |
SDK74266.1 | SDK74230.1 | SAMN04487898_111105 | SAMN04487898_111104 | Hypothetical protein. | Mechanosensitive ion channel. | 0.786 |
SDK74266.1 | gcvP | SAMN04487898_111105 | SAMN04487898_111102 | Hypothetical protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.469 |
SDK74266.1 | pdxJ | SAMN04487898_111105 | SAMN04487898_111103 | Hypothetical protein. | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.622 |
SDL30875.1 | pdxH | SAMN04487898_11734 | SAMN04487898_113129 | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.512 |
SDL30875.1 | pdxJ | SAMN04487898_11734 | SAMN04487898_111103 | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.978 |
SDL85677.1 | pdxJ | SAMN04487898_12676 | SAMN04487898_111103 | Mannose-6-phosphate isomerase, type 2. | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.528 |
dxs | pdxJ | SAMN04487898_102222 | SAMN04487898_111103 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.936 |
gcvP | SDK74230.1 | SAMN04487898_111102 | SAMN04487898_111104 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Mechanosensitive ion channel. | 0.467 |
gcvP | SDK74266.1 | SAMN04487898_111102 | SAMN04487898_111105 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Hypothetical protein. | 0.469 |
gcvP | guaA | SAMN04487898_111102 | SAMN04487898_13010 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.504 |
gcvP | pdxH | SAMN04487898_111102 | SAMN04487898_113129 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.483 |
gcvP | pdxJ | SAMN04487898_111102 | SAMN04487898_111103 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.754 |
guaA | gcvP | SAMN04487898_13010 | SAMN04487898_111102 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.504 |
guaA | pdxJ | SAMN04487898_13010 | SAMN04487898_111103 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.484 |
nnrD | pdxH | SAMN04487898_102141 | SAMN04487898_113129 | yjeF C-terminal region, hydroxyethylthiazole kinase-related; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.622 |
nnrD | pdxJ | SAMN04487898_102141 | SAMN04487898_111103 | yjeF C-terminal region, hydroxyethylthiazole kinase-related; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | Pyridoxine 5-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.703 |