STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFX28643.1Cysteine desulfurase. (387 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 0.995
SFX41332.1
Nitrogen fixation protein NifU.
 
 0.984
SFX46282.1
Cysteine desulfurase.
  
  
 
0.916
SFX28842.1
Ferredoxin.
  
 0.828
SFX52602.1
Molybdopterin or thiamine biosynthesis adenylyltransferase.
   
 0.827
SFX42442.1
Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain.
  
 0.799
SFX72875.1
Cysteine desulfurase.
  
  
 
0.798
SFX21212.1
Transcriptional regulator, BadM/Rrf2 family.
  
 
 0.752
SFX46263.1
Transcriptional regulator, BadM/Rrf2 family.
  
 
 0.752
SFX41290.1
Fe-S cluster assembly ATP-binding protein.
  
 
 0.702
Your Current Organism:
Thermoactinomyces sp. DSM 45891
NCBI taxonomy Id: 1761907
Other names: T. sp. DSM 45891
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.