STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERP0021ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (252 aa)    
Predicted Functional Partners:
SERP0020
ABC transporter, permease protein; Identified by similarity to OMNI:NTL01BH0754; match to protein family HMM PF02687.
 
 0.995
SERP0016
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
 0.977
SERP0315
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
 
 0.885
SERP0951
Peptide ABC transporter, ATP-binding protein, putative; Identified by match to protein family HMM PF00005.
 
    
0.833
SERP2203
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
 
 0.797
graS
Sensor histidine kinase; Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs). GraS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to GraR (By similarity).
 
 
 0.639
SERP0019
Conserved hypothetical protein; Identified by similarity to OMNI:SA2726.
       0.634
SERP1005
ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
 
 0.570
hrtB
ABC transporter, permease protein; Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity).
  
 
 0.570
graR
DNA-binding response regulator; Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).
 
     0.535
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.