STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfrANAD(P)H-flavin oxidoreductase, putative; Reduces FMN, organic nitro compounds and disulfide DTNB. Involved in maintenance of the cellular redox state and the disulfide stress response (By similarity); Belongs to the flavin oxidoreductase frp family. (251 aa)    
Predicted Functional Partners:
ribF
Riboflavin biosynthesis protein RibF; Identified by similarity to SP:P54575; match to protein family HMM PF01687; match to protein family HMM TIGR00083; Belongs to the ribF family.
    
 0.905
SERP0061
2-keto-4-pentenoate hydratase, putative; Identified by match to protein family HMM PF01689.
 
     0.851
birA
birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.537
SERP0887
ABC transporter, permease protein.
  
  
 0.494
SERP2381
NADH:flavin oxidoreductase/fumarate reductase, flavoprotein subunit, putative; Identified by similarity to EGAD:16535; match to protein family HMM PF00724; match to protein family HMM PF00890; match to protein family HMM PF04205; match to protein family HMM TIGR01813.
 
  
 0.490
ribBA
3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
  
 
 0.464
SERP2377
Conserved domain protein.
  
    0.463
vraA
Long chain fatty acid CoA ligase, putative; Identified by match to protein family HMM PF00501; Belongs to the ATP-dependent AMP-binding enzyme family.
   
   0.457
menE
O-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
   
   0.457
perR
Transcriptional regulator, Fur family; Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor (By similarity). Belongs to the Fur family.
  
  
 0.429
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.