STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sle1LysM domain protein; Peptidoglycan hydrolase involved in the splitting of the septum during cell division. (324 aa)    
Predicted Functional Partners:
sceD
sceD protein; Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells; Belongs to the transglycosylase family. SceD subfamily.
     
 0.760
lytH
N-acetylmuramoyl-L-alanine amidase, family 3; Probably involved in cell-wall metabolism; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
  
  
 0.672
atlE
Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
  
  
 0.671
isaA
Immunodominant antigen A, putative; Is able to cleave peptidoglycan; Belongs to the transglycosylase family. IsaA subfamily.
     
 0.498
SERP1640
M23/M37 peptidase domain protein; Identified by match to protein family HMM PF01551; match to protein family HMM TIGR01760.
  
  
 0.474
SERP0439
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.451
SERP0093
Conserved hypothetical protein; Identified by similarity to EGAD:162731.
   
 
 0.438
SERP2263
N-acetylmuramoyl-L-alanine amidase domain protein; Identified by match to protein family HMM PF01832; match to protein family HMM PF05257.
     
0.407
SERP1650
Prophage, amidase, putative; Identified by match to protein family HMM PF01520; match to protein family HMM PF05257.
      
 0.401
sepA
Extracellular elastase precursor; Extracellular zinc metalloprotease.
  
 
 
 0.400
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.