Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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sle1LysM domain protein; Peptidoglycan hydrolase involved in the splitting of the septum during cell division. (324 aa)    
Predicted Functional Partners:
sceD
sceD protein; Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells; Belongs to the transglycosylase family. SceD subfamily.
     
 0.763
atlE
Bifunctional autolysin; Endohydrolysis of the di-N-acetylchitobiosyl unit in high- mannose glycopeptides and glycoproteins containing the -[(Man)5(GlcNAc)2]-Asn structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis (By similarity); In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
  
  
 0.758
lytH
N-acetylmuramoyl-L-alanine amidase, family 3; Probably involved in cell-wall metabolism; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.
  
  
 0.593
isaA
Immunodominant antigen A, putative; Is able to cleave peptidoglycan; Belongs to the transglycosylase family. IsaA subfamily.
     
 0.488
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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