Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SERP0107Transcriptional regulatory protein GltC, putative; Identified by similarity to EGAD:6257; match to protein family HMM PF00126; Belongs to the LysR transcriptional regulatory family. (293 aa)    
Predicted Functional Partners:
SERP0110
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.765
SERP0328
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.761
SERP0105
Conserved hypothetical protein; Identified by similarity to OMNI:SA0511.
       0.734
SERP0106
Conserved hypothetical protein; Identified by similarity to OMNI:SA0512.
       0.734
SERP2233
Transcriptional regulator, LysR family; Identified by match to protein family HMM PF00126; Belongs to the LysR transcriptional regulatory family.
  
     0.718
gltD
Glutamate synthase, small subunit; Identified by match to protein family HMM PF00070; match to protein family HMM TIGR01317.
   
 
 0.537
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
      
 0.489
SERP0595
Daunorubicin resistance protein DrrC, putative; Identified by similarity to EGAD:39654; match to protein family HMM PF00005.
       0.483
arcR
Transcriptional regulator, Crp/Fnr family; Positively regulates the expression of the arcABDCR operon under anaerobic conditions, thus playing an essential role in arginine catabolism. May also control the expression of genes encoding proteins which are involved in anaerobic metabolism. Can bind cyclic AMP (By similarity).
  
 
 0.453
SERP1931
DNA-3-methyladenine glycosylase; Identified by match to protein family HMM PF02245; match to protein family HMM TIGR00567; Belongs to the DNA glycosylase MPG family.
       0.447
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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