Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gltDGlutamate synthase, small subunit; Identified by match to protein family HMM PF00070; match to protein family HMM TIGR01317. (487 aa)    
Predicted Functional Partners:
SERP2041
Glutamate synthase-related protein; Identified by match to protein family HMM PF01645; Belongs to the glutamate synthase family.
 
 0.998
femC
Glutamine synthetase FemC; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback- inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation. U [...]
  
 
 0.985
SERP0856
Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855.
    
 0.942
gluD
Glutamate dehydrogenase, NAD-specific; Identified by similarity to EGAD:20751; match to protein family HMM PF00208; match to protein family HMM PF02812; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.935
glmS
Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.935
carB
Carbamoyl-phosphate synthase, large subunit; Identified by similarity to EGAD:19162; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369.
  
 
 0.916
SERP1488
Hydrolase, carbon-nitrogen family; Identified by match to protein family HMM PF00795.
  
 0.916
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.909
rocA
Delta-1-pyrroline-5-carboxylate dehydrogenase, putative; Identified by similarity to EGAD:22788; match to protein family HMM PF00171; match to protein family HMM TIGR01237; Belongs to the aldehyde dehydrogenase family. RocA subfamily.
   
 0.909
carA
Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family.
    
  0.904
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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