mvaD protein (Staphylococcus epidermidis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

mvaD

Mevalonate diphosphate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01240. (327 aa)

Predicted Functional Partners:

SERP0240

0.999

mvk

0.993

fni-2

0.988

ispA

0.950

SERP2122

0.939

SERP2121

0.888

SERP0241

0.694

lysS

0.658

SERP2525

0.536

SERP1038

0.528

Your Current Organism:

Staphylococcus epidermidis

NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SERP0240	SERP0241	SERP0240	SERP0241	Phosphomevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01220.	Conserved hypothetical protein; Identified by similarity to OMNI:SA0639; Belongs to the UPF0741 family.	0.704
SERP0240	SERP2121	SERP0240	SERP2121	Phosphomevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01220.	hydroxymethylglutaryl-CoA reductase, degradative; Identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.	0.836
SERP0240	SERP2122	SERP0240	SERP2122	Phosphomevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01220.	hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM TIGR01835.	0.899
SERP0240	fni-2	SERP0240	SERP1937	Phosphomevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01220.	Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).	0.965
SERP0240	mvaD	SERP0240	SERP0239	Phosphomevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01220.	Mevalonate diphosphate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01240.	0.999
SERP0240	mvk	SERP0240	SERP0238	Phosphomevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01220.	Mevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR00549.	0.998
SERP0241	SERP0240	SERP0241	SERP0240	Conserved hypothetical protein; Identified by similarity to OMNI:SA0639; Belongs to the UPF0741 family.	Phosphomevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01220.	0.704
SERP0241	mvaD	SERP0241	SERP0239	Conserved hypothetical protein; Identified by similarity to OMNI:SA0639; Belongs to the UPF0741 family.	Mevalonate diphosphate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01240.	0.694
SERP0241	mvk	SERP0241	SERP0238	Conserved hypothetical protein; Identified by similarity to OMNI:SA0639; Belongs to the UPF0741 family.	Mevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR00549.	0.694
SERP1038	SERP2121	SERP1038	SERP2121	Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.	hydroxymethylglutaryl-CoA reductase, degradative; Identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.	0.481
SERP1038	fni-2	SERP1038	SERP1937	Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.	Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).	0.479
SERP1038	ispA	SERP1038	SERP1082	Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.	Geranyltranstransferase; Identified by similarity to SP:Q08291; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.	0.918
SERP1038	mvaD	SERP1038	SERP0239	Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.	Mevalonate diphosphate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01240.	0.528
SERP2121	SERP0240	SERP2121	SERP0240	hydroxymethylglutaryl-CoA reductase, degradative; Identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.	Phosphomevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01220.	0.836
SERP2121	SERP1038	SERP2121	SERP1038	hydroxymethylglutaryl-CoA reductase, degradative; Identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.	Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.	0.481
SERP2121	SERP2122	SERP2121	SERP2122	hydroxymethylglutaryl-CoA reductase, degradative; Identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.	hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM TIGR01835.	0.998
SERP2121	SERP2525	SERP2121	SERP2525	hydroxymethylglutaryl-CoA reductase, degradative; Identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.	HMG-CoA synthase, truncation; Identified by similarity to GP:9937361.	0.651
SERP2121	fni-2	SERP2121	SERP1937	hydroxymethylglutaryl-CoA reductase, degradative; Identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.	Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).	0.887
SERP2121	ispA	SERP2121	SERP1082	hydroxymethylglutaryl-CoA reductase, degradative; Identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.	Geranyltranstransferase; Identified by similarity to SP:Q08291; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.	0.763
SERP2121	mvaD	SERP2121	SERP0239	hydroxymethylglutaryl-CoA reductase, degradative; Identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.	Mevalonate diphosphate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01240.	0.888

page 1 of 3

Server load: low (12%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About