sirR protein (Staphylococcus epidermidis) - STRING interaction network

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Score

sirR

Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742. (214 aa)

Predicted Functional Partners:

sitB

0.974

sitA

0.974

sitC

0.965

SERP1407

0.760

SERP1771

0.760

mntH

0.725

fur

0.644

tpx

0.519

SERP0438

0.477

metN1

0.410

Your Current Organism:

Staphylococcus epidermidis

NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SERP0438	sirR	SERP0438	SERP0293	Identified by match to protein family HMM TIGR01777; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	0.477
SERP1407	sirR	SERP1407	SERP0293	Conserved hypothetical protein; Identified by similarity to OMNI:SA1927; match to protein family HMM PF04307.	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	0.760
SERP1771	sirR	SERP1771	SERP0293	Conserved hypothetical protein; Identified by match to protein family HMM PF04307.	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	0.760
fur	sirR	SERP1120	SERP0293	Transcriptional regulator, Fur family; Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	0.644
metN1	sirR	SERP0097	SERP0293	ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	0.410
mntH	sirR	SERP0692	SERP0293	Mn2+/Fe2+ transporter, NRAMP family; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	0.725
mntH	sitA	SERP0692	SERP0292	Mn2+/Fe2+ transporter, NRAMP family; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.	ABC transporter, ATP-binding protein; Identified by similarity to GP:1617428; match to protein family HMM PF00005.	0.598
mntH	sitB	SERP0692	SERP0291	Mn2+/Fe2+ transporter, NRAMP family; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.	ABC transporter, permease protein; Identified by match to protein family HMM PF00950.	0.836
mntH	sitC	SERP0692	SERP0290	Mn2+/Fe2+ transporter, NRAMP family; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.	ABC transporter, substrate-binding protein; Identified by similarity to GP:1617430; match to protein family HMM PF01297; Belongs to the bacterial solute-binding protein 9 family.	0.609
sirR	SERP0438	SERP0293	SERP0438	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	Identified by match to protein family HMM TIGR01777; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.	0.477
sirR	SERP1407	SERP0293	SERP1407	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	Conserved hypothetical protein; Identified by similarity to OMNI:SA1927; match to protein family HMM PF04307.	0.760
sirR	SERP1771	SERP0293	SERP1771	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	Conserved hypothetical protein; Identified by match to protein family HMM PF04307.	0.760
sirR	fur	SERP0293	SERP1120	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	Transcriptional regulator, Fur family; Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.	0.644
sirR	metN1	SERP0293	SERP0097	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.	0.410
sirR	mntH	SERP0293	SERP0692	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	Mn2+/Fe2+ transporter, NRAMP family; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.	0.725
sirR	sitA	SERP0293	SERP0292	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	ABC transporter, ATP-binding protein; Identified by similarity to GP:1617428; match to protein family HMM PF00005.	0.974
sirR	sitB	SERP0293	SERP0291	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	ABC transporter, permease protein; Identified by match to protein family HMM PF00950.	0.974
sirR	sitC	SERP0293	SERP0290	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	ABC transporter, substrate-binding protein; Identified by similarity to GP:1617430; match to protein family HMM PF01297; Belongs to the bacterial solute-binding protein 9 family.	0.965
sirR	tpx	SERP0293	SERP1277	Iron-dependent repressor; Identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742.	Thiol peroxidase, putative; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.	0.519
sitA	mntH	SERP0292	SERP0692	ABC transporter, ATP-binding protein; Identified by similarity to GP:1617428; match to protein family HMM PF00005.	Mn2+/Fe2+ transporter, NRAMP family; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.	0.598

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