Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fruAPTS system, fructose-specific IIABC components; Identified by similarity to GP:9501781; match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427. (650 aa)    
Predicted Functional Partners:
fruK
1-phosphofructokinase; Identified by similarity to EGAD:107874; match to protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.999
lacC
Tagatose-6-phosphate kinase; Identified by similarity to EGAD:6991; match to protein family HMM PF00294; match to protein family HMM TIGR01231; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.998
ptsH
Phosphocarrier protein HPr; Identified by similarity to EGAD:6430; match to protein family HMM PF00381; match to protein family HMM TIGR01003.
 
 
 0.989
SERP0357
Transcriptional regulator, DeoR family; Identified by match to protein family HMM PF00455.
 
  
 0.980
fbaA
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.978
ptsG
PTS system, IIABC components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.
  
  
 0.970
lacR
Lactose phosphotransferase system repressor; Repressor of the lactose catabolism operon. Galactose-6- phosphate is the inducer (By similarity).
 
  
 0.957
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.934
SERP1494
Fructokinase, putative; Identified by match to protein family HMM PF00294.
    
 0.933
SERP2260
PTS system, fructose-specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
 
  
0.914
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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