Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SERP0367Lipoprotein, putative. (145 aa)    
Predicted Functional Partners:
SERP0366
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01BH2256.
 
     0.860
saeR
DNA-binding response regulator SaeR; Member of the two-component regulatory system SaeR/SaeS. Probably functions as a transcriptional regulator via a specific DNA- binding domain, recognizing motifs near the promoter sequences of target genes (By similarity).
       0.652
SERP2504
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA0058.
  
     0.549
saeS
Sensor histidine kinase SaeS; Member of the two-component regulatory system SaeR/SaeS. Probably functions as a membrane-associated protein kinase that upon sensing the appropriate signal, autophosphorylates and in turn activates the cytosolic response regulator SaeR (By similarity).
       0.546
SERP2496
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA0063.
  
     0.545
SERP2279
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA2544.
  
     0.518
SERP2467
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA0058.
  
     0.516
SERP0207
sdrG protein; Point mutation observed 38 residues upstream of the start, causing translation to begin at the Leu; identified by similarity to GP:8101007; match to protein family HMM PF00746; match to protein family HMM PF05738; match to protein family HMM TIGR01167.
  
     0.482
SERP1453
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA1794.
  
     0.433
isdG
Conserved hypothetical protein; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
  
     0.403
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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