Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SERP0551Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA0852. (191 aa)    
Predicted Functional Partners:
spsA
Signal peptidase IA, inactive; Identified by similarity to SP:P72364; match to protein family HMM PF00461; Belongs to the peptidase S26 family.
  
    0.883
spsB
Signal peptidase IB; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family.
  
    0.763
rexB
Exonuclease RexB; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
 
     0.726
SERP0980
Conserved hypothetical protein; Identified by similarity to OMNI:SA1446.
  
     0.712
traP
RNAIII-activating protein TRAP; Contributes to virulence and biofilm formation.
 
     0.705
rexA
Exonuclease RexA; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily.
 
     0.666
SERP0214
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA0545.
 
     0.643
SERP0618
ComK family protein.
 
     0.640
SERP0557
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA0858.
 
     0.559
pgi
Glucose-6-phosphate isomerase; Identified by similarity to EGAD:10310; match to protein family HMM PF00342.
       0.529
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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