Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SERP0590Na+/H+ exchanger family protein, putative; Identified by match to protein family HMM PF00999; match to protein family HMM PF02080; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (614 aa)    
Predicted Functional Partners:
mgtE
Magnesium transporter; Acts as a magnesium transporter.
     
 0.927
SERP0458
Identified by match to protein family HMM PF02386.
  
 
 0.833
SERP0612
Identified by match to protein family HMM PF02386.
  
 
 0.833
sun
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
   0.771
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.769
SERP0856
Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855.
  
 
 0.753
nadK
Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.749
SERP0588
Ribosomal large subunit pseudouridine synthase, RluD subfamily; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
    0.740
relA-1
GTP pyrophosphokinase; Identified by match to protein family HMM PF04607.
       0.713
SERP0583
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA0892; match to protein family HMM PF01928.
       0.700
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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