STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERP0668Conserved hypothetical protein; Identified by similarity to OMNI:SA1090. (179 aa)    
Predicted Functional Partners:
SERP0667
Conserved hypothetical protein; Identified by similarity to OMNI:SA1089.
       0.845
ptsH
Phosphocarrier protein HPr; Identified by similarity to EGAD:6430; match to protein family HMM PF00381; match to protein family HMM TIGR01003.
       0.799
ptsI
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
       0.799
yvcD
yvcD protein; Identified by similarity to GP:5690062; match to protein family HMM PF00515.
 
     0.729
SERP0329
Sugar efflux transporter, putative; Identified by similarity to EGAD:6822; similarity to EGAD:7093; similarity to EGAD:19549.
  
     0.728
SERP1733
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA2005.
  
     0.697
SERP0327
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA0647; match to protein family HMM PF04167.
  
     0.685
ltaA
Membrane protein, putative; Probable permease that is required for glycolipid anchoring of LTA. May facilitate the transport of diglucosyl-diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of the cytoplasmic membrane, delivering Glc2-DAG as a substrate for LTA synthesis, thereby generating glycolipid-anchored LTA. Appears to play an important role in virulence (By similarity); Belongs to the major facilitator superfamily. LtaA family.
  
     0.680
SERP1212
Rod shape-determining protein MreD, putative; Identified by match to protein family HMM PF04093.
 
     0.642
ebpS
Elastin binding protein, putative; Identified by match to protein family HMM PF01476.
  
     0.640
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.