STRINGSTRING
pdhC protein (Staphylococcus epidermidis RP62A) - STRING interaction network
"pdhC" - Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex in Staphylococcus epidermidis RP62A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhCDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components- pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (433 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components- pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity) (370 aa)
 
  0.999
pdhD
Dihydrolipoyl dehydrogenase; Identified by similarity to EGAD-23102; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350 (468 aa)
  0.999
pdhB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components- pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity) (325 aa)
 
  0.999
SERP1078
2-oxoisovalerate dehydrogenase, E1 component, alpha subunit; Identified by similarity to EGAD-21637; match to protein family HMM PF00676 (332 aa)
 
  0.986
SERP1077
2-oxoisovalerate dehydrogenase, E1 component, beta subunit; Identified by similarity to EGAD-21712; match to protein family HMM PF02779; match to protein family HMM PF02780 (327 aa)
 
  0.984
lpdA
Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350 (473 aa)
  0.977
SERP2327
Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350 (450 aa)
  0.975
SERP2325
Acetoin dehydrogenase, E1 component, beta subunit; Identified by similarity to SP-O34591; match to protein family HMM PF02779; match to protein family HMM PF02780 (346 aa)
 
  0.961
SERP2326
Acetoin dehydrogenase, E1 component, alpha subunit; Identified by similarity to SP-P27745; match to protein family HMM PF00676 (317 aa)
 
  0.961
gltA
Citrate synthase; Identified by similarity to EGAD-21870; match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family (373 aa)
   
  0.959
Your Current Organism:
Staphylococcus epidermidis RP62A
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
Server load: low (11%) [HD]