Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Experiments
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[Homology]
Score
SERP0690Conserved hypothetical protein; Identified by similarity to OMNI:SA1112. (383 aa)    
Predicted Functional Partners:
potA
Spermidine/putrescine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
       0.777
potB
Spermidine/putrescine ABC transporter, permease protein PotB; Identified by similarity to EGAD:24120; match to protein family HMM PF00528.
       0.777
potC
Spermidine/putrescine ABC transporter, permease protein PotC; Identified by similarity to EGAD:15490; match to protein family HMM PF00528.
       0.777
potD
Spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein; Identified by similarity to EGAD:16715; match to protein family HMM PF01547.
       0.777
SERP0685
Transcriptional regulator, Cro/CI family; Identified by match to protein family HMM PF01381.
       0.769
SERP0684
Conserved hypothetical protein; Identified by similarity to OMNI:SA1106; match to protein family HMM PF05256; Belongs to the UPF0223 family.
       0.671
SERP0691
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA0989.
       0.555
pdhC
Pyruvate dehydrogenase complex E2 component, dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
       0.522
pdhD
Pyruvate dehydrogenase complex E3 component, lipoamide dehydrogenase; Identified by similarity to EGAD:23102; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350.
       0.522
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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