| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carB | pyrB | SERP0769 | SERP0766 | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to EGAD:19162; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | Aspartate carbamoyltransferase; Identified by similarity to EGAD:16102; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| carB | pyrC | SERP0769 | SERP0767 | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to EGAD:19162; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
| carB | pyrE | SERP0769 | SERP0771 | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to EGAD:19162; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.997 |
| carB | pyrF | SERP0769 | SERP0770 | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to EGAD:19162; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.998 |
| carB | pyrR | SERP0769 | SERP0764 | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to EGAD:19162; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | Pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.992 |
| carB | udk | SERP0769 | SERP1175 | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to EGAD:19162; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | Uridine kinase; Identified by similarity to EGAD:110007; match to protein family HMM PF00485; match to protein family HMM TIGR00235. | 0.481 |
| carB | uraA | SERP0769 | SERP0765 | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to EGAD:19162; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | Uracil permease; Identified by similarity to EGAD:18534; match to protein family HMM PF00860; match to protein family HMM TIGR00801. | 0.989 |
| pdp | pyrR | SERP1744 | SERP0764 | Pyrimidine-nucleoside phosphorylase; Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.916 |
| pdp | udk | SERP1744 | SERP1175 | Pyrimidine-nucleoside phosphorylase; Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Uridine kinase; Identified by similarity to EGAD:110007; match to protein family HMM PF00485; match to protein family HMM TIGR00235. | 0.946 |
| pdp | upp | SERP1744 | SERP1718 | Pyrimidine-nucleoside phosphorylase; Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.929 |
| pyrB | carB | SERP0766 | SERP0769 | Aspartate carbamoyltransferase; Identified by similarity to EGAD:16102; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to EGAD:19162; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | 0.999 |
| pyrB | pyrC | SERP0766 | SERP0767 | Aspartate carbamoyltransferase; Identified by similarity to EGAD:16102; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
| pyrB | pyrE | SERP0766 | SERP0771 | Aspartate carbamoyltransferase; Identified by similarity to EGAD:16102; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.997 |
| pyrB | pyrF | SERP0766 | SERP0770 | Aspartate carbamoyltransferase; Identified by similarity to EGAD:16102; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.998 |
| pyrB | pyrH | SERP0766 | SERP0825 | Aspartate carbamoyltransferase; Identified by similarity to EGAD:16102; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.715 |
| pyrB | pyrR | SERP0766 | SERP0764 | Aspartate carbamoyltransferase; Identified by similarity to EGAD:16102; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.997 |
| pyrB | udk | SERP0766 | SERP1175 | Aspartate carbamoyltransferase; Identified by similarity to EGAD:16102; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uridine kinase; Identified by similarity to EGAD:110007; match to protein family HMM PF00485; match to protein family HMM TIGR00235. | 0.472 |
| pyrB | upp | SERP0766 | SERP1718 | Aspartate carbamoyltransferase; Identified by similarity to EGAD:16102; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.757 |
| pyrB | uraA | SERP0766 | SERP0765 | Aspartate carbamoyltransferase; Identified by similarity to EGAD:16102; match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | Uracil permease; Identified by similarity to EGAD:18534; match to protein family HMM PF00860; match to protein family HMM TIGR00801. | 0.996 |
| pyrC | carB | SERP0767 | SERP0769 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase, large subunit; Identified by similarity to EGAD:19162; match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369. | 0.999 |
