STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERP0874Conserved hypothetical protein; Identified by similarity to OMNI:SA1327. (412 aa)    
Predicted Functional Partners:
hflX
GTP-binding protein, putative; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
 
    0.903
gpxA-1
Glutathione peroxidase; Identified by similarity to EGAD:45646; match to protein family HMM PF00255; Belongs to the glutathione peroxidase family.
       0.817
SERP0119
Orn/Lys/Arg decarboxylase; Identified by match to protein family HMM PF01276.
 
   
 0.756
ddl
D-alanine--D-alanine ligase; Cell wall formation.
      0.730
ylmF
ylmF protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
 
     0.658
glnR
Glutamine synthetase repressor; Identified by similarity to EGAD:15799; match to protein family HMM PF00376.
       0.636
femC
Glutamine synthetase FemC; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback- inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation. U [...]
       0.636
SERP1181
Conserved hypothetical protein; Identified by similarity to OMNI:SA1672; Belongs to the UPF0297 family.
 
     0.514
SERP1486
Identified by match to protein family HMM PF02517.
  
     0.488
SERP0847
Short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF00678.
  
     0.422
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.