STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
katACatalase; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (504 aa)    
Predicted Functional Partners:
ahpC
Alkyl hydroperoxide reductase, C subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.736
sodA
Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 0.696
SERP2522
MaoC domain protein; Identified by match to protein family HMM PF01575.
   
 0.696
hfq
Host factor-I protein, putative; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
    
 
 0.683
rpmG-2
Ribosomal protein L33; Identified by match to protein family HMM PF00471; match to protein family HMM TIGR01023; Belongs to the bacterial ribosomal protein bL33 family.
       0.592
SERP1866
acyl-CoA dehydrogenase-related protein; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770.
  
 0.566
SERP0902
Amino acid permease family protein; Identified by match to protein family HMM PF00324.
       0.531
ahpF
Alkyl hydroperoxide reductase, F subunit; Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein (By similarity); Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
  
  
 0.496
SERP0944
Identified by match to protein family HMM PF01965.
  
 
 0.491
SERP1413
Identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382; Belongs to the peptidase C56 family.
  
 
 0.491
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.