Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
SERP0907Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA1219; match to protein family HMM PF00188. (341 aa)    
Predicted Functional Partners:
guaC
Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
       0.859
SERP0908
Hypothetical protein; Identified by Glimmer2; putative.
       0.603
sdrH
sdrH protein; Identified by similarity to GP:8101009.
 
    0.532
SERP0726
DNA-dependent DNA polymerase family X; Identified by match to protein family HMM PF00966; match to protein family HMM PF02231; match to protein family HMM PF02811.
  
    0.510
rpsN-1
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
   
   0.502
rsbW
Anti-sigma B factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
  
     0.500
SERP0064
Conserved hypothetical protein; Identified by similarity to OMNI:SA0455.
  
    0.448
SERP1635
Conserved hypothetical protein; Identified by similarity to EGAD:107782.
   
    0.446
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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