dapD protein (Staphylococcus epidermidis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

dapD

2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (240 aa)

Predicted Functional Partners:

dapB

0.999

dapA

0.993

asd

0.991

lysA

0.952

SERP0633

0.935

lysC

0.926

SERP0968

0.863

SERP0969

0.794

SERP0896

0.691

guaA

0.681

Your Current Organism:

Staphylococcus epidermidis

NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SERP0633	SERP0896	SERP0633	SERP0896	Aminotransferase, class I; Identified by match to protein family HMM PF00155.	Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.	0.500
SERP0633	asd	SERP0633	SERP0964	Aminotransferase, class I; Identified by match to protein family HMM PF00155.	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	0.536
SERP0633	dapA	SERP0633	SERP0965	Aminotransferase, class I; Identified by match to protein family HMM PF00155.	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.516
SERP0633	dapD	SERP0633	SERP0967	Aminotransferase, class I; Identified by match to protein family HMM PF00155.	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.	0.935
SERP0633	lysA	SERP0633	SERP0970	Aminotransferase, class I; Identified by match to protein family HMM PF00155.	Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.	0.486
SERP0896	SERP0633	SERP0896	SERP0633	Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.	Aminotransferase, class I; Identified by match to protein family HMM PF00155.	0.500
SERP0896	asd	SERP0896	SERP0964	Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	0.986
SERP0896	dapA	SERP0896	SERP0965	Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.688
SERP0896	dapB	SERP0896	SERP0966	Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.	Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.	0.549
SERP0896	dapD	SERP0896	SERP0967	Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.	0.691
SERP0896	lysA	SERP0896	SERP0970	Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.	Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.	0.876
SERP0896	lysC	SERP0896	SERP0963	Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.	Aspartokinase, alpha and beta subunits; Identified by similarity to SP:P08495; match to protein family HMM PF00696; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.	0.900
SERP0968	SERP0969	SERP0968	SERP0969	Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20 family.	Alanine racemase family protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.	0.875
SERP0968	asd	SERP0968	SERP0964	Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20 family.	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	0.747
SERP0968	dapA	SERP0968	SERP0965	Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20 family.	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.711
SERP0968	dapB	SERP0968	SERP0966	Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20 family.	Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.	0.738
SERP0968	dapD	SERP0968	SERP0967	Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20 family.	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.	0.863
SERP0968	lysA	SERP0968	SERP0970	Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20 family.	Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.	0.888
SERP0968	lysC	SERP0968	SERP0963	Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20 family.	Aspartokinase, alpha and beta subunits; Identified by similarity to SP:P08495; match to protein family HMM PF00696; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.	0.661
SERP0969	SERP0968	SERP0969	SERP0968	Alanine racemase family protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.	Identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; Belongs to the peptidase M20 family.	0.875

page 1 of 5

Server load: medium (42%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About