| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SERP0973 | cspA | SERP0973 | SERP0972 | Conserved hypothetical protein; Identified by similarity to OMNI:SA1438. | Cold shock protein, CSD family; Involved in cold stress response. | 0.729 |
| cshA | cspA | SERP1688 | SERP0972 | ATP-dependent RNA helicase, DEAD/DEAH box family; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. | Cold shock protein, CSD family; Involved in cold stress response. | 0.563 |
| cshA | dnaJ | SERP1688 | SERP1147 | ATP-dependent RNA helicase, DEAD/DEAH box family; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. | dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.733 |
| cshA | dnaK | SERP1688 | SERP1148 | ATP-dependent RNA helicase, DEAD/DEAH box family; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. | dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.660 |
| cshA | rpsL | SERP1688 | SERP0186 | ATP-dependent RNA helicase, DEAD/DEAH box family; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.455 |
| cshA | rpsQ | SERP1688 | SERP1822 | ATP-dependent RNA helicase, DEAD/DEAH box family; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. | Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.546 |
| cshB | cspA | SERP1124 | SERP0972 | ATP-dependent RNA helicase, DEAD/DEAH box family; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. | Cold shock protein, CSD family; Involved in cold stress response. | 0.566 |
| cshB | dnaJ | SERP1124 | SERP1147 | ATP-dependent RNA helicase, DEAD/DEAH box family; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. | dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.561 |
| cshB | dnaK | SERP1124 | SERP1148 | ATP-dependent RNA helicase, DEAD/DEAH box family; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. | dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.504 |
| cshB | rpsL | SERP1124 | SERP0186 | ATP-dependent RNA helicase, DEAD/DEAH box family; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.455 |
| cshB | rpsQ | SERP1124 | SERP1822 | ATP-dependent RNA helicase, DEAD/DEAH box family; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. | Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.546 |
| cspA | SERP0973 | SERP0972 | SERP0973 | Cold shock protein, CSD family; Involved in cold stress response. | Conserved hypothetical protein; Identified by similarity to OMNI:SA1438. | 0.729 |
| cspA | cshA | SERP0972 | SERP1688 | Cold shock protein, CSD family; Involved in cold stress response. | ATP-dependent RNA helicase, DEAD/DEAH box family; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. | 0.563 |
| cspA | cshB | SERP0972 | SERP1124 | Cold shock protein, CSD family; Involved in cold stress response. | ATP-dependent RNA helicase, DEAD/DEAH box family; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. | 0.566 |
| cspA | dnaJ | SERP0972 | SERP1147 | Cold shock protein, CSD family; Involved in cold stress response. | dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.679 |
| cspA | dnaK | SERP0972 | SERP1148 | Cold shock protein, CSD family; Involved in cold stress response. | dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.765 |
| cspA | grpE | SERP0972 | SERP1149 | Cold shock protein, CSD family; Involved in cold stress response. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.715 |
| cspA | hrcA | SERP0972 | SERP1150 | Cold shock protein, CSD family; Involved in cold stress response. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.667 |
| cspA | rpsL | SERP0972 | SERP0186 | Cold shock protein, CSD family; Involved in cold stress response. | Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.589 |
| cspA | rpsQ | SERP0972 | SERP1822 | Cold shock protein, CSD family; Involved in cold stress response. | Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.586 |
