Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SERP0983Hypothetical protein; Identified by Glimmer2; putative. (233 aa)    
Predicted Functional Partners:
SERP0984
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
       0.875
SERP2374
Conserved hypothetical protein; Identified by similarity to OMNI:SA2478.
  
   0.669
sdrH
sdrH protein; Identified by similarity to GP:8101009.
  
     0.579
SERP2540
Membrane protein, putative; Identified by similarity to OMNI:NTL01SA0014.
  
     0.540
SERP2264
Cell wall surface anchor family protein.
  
     0.531
isdG
Conserved hypothetical protein; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo- beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
  
     0.528
sucB
2-oxoglutarate dehydrogenase, E2 component, dihydroipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
   
   0.520
SERP2375
Diaminopimelate epimerase family protein.
  
     0.485
SERP0241
Conserved hypothetical protein; Identified by similarity to OMNI:SA0639; Belongs to the UPF0741 family.
  
     0.478
sucA
2-oxoglutarate dehydrogenase, E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
       0.474
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.