Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cmkCytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. (215 aa)    
Predicted Functional Partners:
der
GTP-binding protein, Era/TrmE family; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
 0.985
rpsA
Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
 
  
 0.955
udk
Uridine kinase; Identified by similarity to EGAD:110007; match to protein family HMM PF00485; match to protein family HMM TIGR00235.
   
 
 0.943
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 
 0.924
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
    
 0.918
SERP1513
Truncated ribonucleoside-diphosphate reductase 2, alpha subunit; Contains a 384 residue intein; identified by match to protein family HMM PF00317; match to protein family HMM PF02867; match to protein family HMM TIGR01443; match to protein family HMM TIGR01445; may be nonfunctional due to interuption.
  
 
 0.916
nrdE
Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.914
nrdF-1
Ribonucleoside-diphosphate reductase 2, beta subunit; Identified by similarity to EGAD:37758; match to protein family HMM PF00268.
    
 0.910
nrdF-2
Ribonucleoside-diphosphate reductase 2, beta subunit; Identified by similarity to EGAD:37758; match to protein family HMM PF00268.
    
 0.910
SERP0202
Identified by match to protein family HMM PF01712.
   
 
  0.907
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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