Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
malAAlpha-glucosidase; Identified by match to protein family HMM PF00128. (551 aa)    
Predicted Functional Partners:
cscA
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
 
 0.956
SERP1494
Fructokinase, putative; Identified by match to protein family HMM PF00294.
 
 
 0.928
ptsG
PTS system, IIABC components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.
  
  
 0.909
SERP2121
hydroxymethylglutaryl-CoA reductase, degradative; Identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.
   
  
 0.788
SERP1968
PTS system, sucrose-specific IIBC components; Identified by similarity to EGAD:18969; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826.
 
  
 0.767
fruA
PTS system, fructose-specific IIABC components; Identified by similarity to GP:9501781; match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
     
 0.644
SERP2260
PTS system, fructose-specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
     
 0.644
pyk
Pyruvate kinase; Identified by similarity to EGAD:37614; match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
  
 
 0.572
SERP0232
Amino acid permease family protein; Identified by match to protein family HMM PF00324.
   
 0.550
SERP2018
Membrane protein, putative; Identified by match to protein family HMM PF00324.
   
 0.550
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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