STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERP1121ABC transporter, permease protein; Identified by match to protein family HMM PF00950. (282 aa)    
Predicted Functional Partners:
SERP1122
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
 
 0.999
SERP2081
Adhesion lipoprotein, putative; Identified by match to protein family HMM PF01297; Belongs to the bacterial solute-binding protein 9 family.
 
 
 0.978
SERP2383
ABC transporter, substrate-binding protein; Identified by match to protein family HMM PF01297; Belongs to the bacterial solute-binding protein 9 family.
 
 
 0.978
sitA
ABC transporter, ATP-binding protein; Identified by similarity to GP:1617428; match to protein family HMM PF00005.
 
 
 0.945
fur
Transcriptional regulator, Fur family; Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
  
  
 0.921
sitC
ABC transporter, substrate-binding protein; Identified by similarity to GP:1617430; match to protein family HMM PF01297; Belongs to the bacterial solute-binding protein 9 family.
  
 0.892
nfo
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
  
    0.793
cshB
ATP-dependent RNA helicase, DEAD/DEAH box family; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.
  
    0.770
sodA
Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
     
 0.665
SERP1126
Conserved hypothetical protein; Identified by similarity to OMNI:SA1617; match to protein family HMM PF04816.
       0.534
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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