| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SERP0135 | apt | SERP0135 | SERP1198 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.732 |
| SERP0752 | apt | SERP0752 | SERP1198 | Conserved hypothetical protein TIGR00726; Multicopper oxidase with polyphenol oxidase activity. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.903 |
| SERP0752 | deoD | SERP0752 | SERP1747 | Conserved hypothetical protein TIGR00726; Multicopper oxidase with polyphenol oxidase activity. | Purine nucleoside phosphorylase; Identified by match to protein family HMM PF01048; match to protein family HMM TIGR00107. | 0.900 |
| adk | apt | SERP1810 | SERP1198 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.929 |
| adk | guaA | SERP1810 | SERP0070 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.714 |
| adk | purB | SERP1810 | SERP1446 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenylosuccinate lyase; Identified by similarity to EGAD:15453; match to protein family HMM PF00206; match to protein family HMM TIGR00928. | 0.942 |
| apt | SERP0135 | SERP1198 | SERP0135 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | 0.732 |
| apt | SERP0752 | SERP1198 | SERP0752 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Conserved hypothetical protein TIGR00726; Multicopper oxidase with polyphenol oxidase activity. | 0.903 |
| apt | adk | SERP1198 | SERP1810 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.929 |
| apt | deoD | SERP1198 | SERP1747 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Purine nucleoside phosphorylase; Identified by match to protein family HMM PF01048; match to protein family HMM TIGR00107. | 0.924 |
| apt | guaA | SERP1198 | SERP0070 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.765 |
| apt | hisF | SERP1198 | SERP2301 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.814 |
| apt | hisH | SERP1198 | SERP2303 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Amidotransferase HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.808 |
| apt | purB | SERP1198 | SERP1446 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate lyase; Identified by similarity to EGAD:15453; match to protein family HMM PF00206; match to protein family HMM TIGR00928. | 0.966 |
| apt | purH | SERP1198 | SERP0658 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. | 0.966 |
| apt | recJ | SERP1198 | SERP1199 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | single-stranded-DNA-specific exonuclease RecJ; Identified by similarity to EGAD:24228; match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644. | 0.879 |
| deoD | SERP0752 | SERP1747 | SERP0752 | Purine nucleoside phosphorylase; Identified by match to protein family HMM PF01048; match to protein family HMM TIGR00107. | Conserved hypothetical protein TIGR00726; Multicopper oxidase with polyphenol oxidase activity. | 0.900 |
| deoD | apt | SERP1747 | SERP1198 | Purine nucleoside phosphorylase; Identified by match to protein family HMM PF01048; match to protein family HMM TIGR00107. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.924 |
| guaA | adk | SERP0070 | SERP1810 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.714 |
| guaA | apt | SERP0070 | SERP1198 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.765 |
