| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SERP1207 | SERP1210 | SERP1207 | SERP1210 | ACT domain protein; Identified by match to protein family HMM PF01842; Belongs to the UPF0735 family. | Conserved hypothetical protein; Identified by similarity to OMNI:SA1701; match to protein family HMM PF04327. | 0.824 |
| SERP1207 | obg | SERP1207 | SERP1208 | ACT domain protein; Identified by match to protein family HMM PF01842; Belongs to the UPF0735 family. | GTP-binding protein, GTP1/OBG family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.891 |
| SERP1207 | queA | SERP1207 | SERP1204 | ACT domain protein; Identified by match to protein family HMM PF01842; Belongs to the UPF0735 family. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.877 |
| SERP1207 | rpmA | SERP1207 | SERP1209 | ACT domain protein; Identified by match to protein family HMM PF01842; Belongs to the UPF0735 family. | Ribosomal protein L27; Identified by match to protein family HMM PF01016; match to protein family HMM TIGR00062; Belongs to the bacterial ribosomal protein bL27 family. | 0.800 |
| SERP1207 | ruvA | SERP1207 | SERP1206 | ACT domain protein; Identified by match to protein family HMM PF01842; Belongs to the UPF0735 family. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.880 |
| SERP1207 | ruvB | SERP1207 | SERP1205 | ACT domain protein; Identified by match to protein family HMM PF01842; Belongs to the UPF0735 family. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.877 |
| SERP1207 | tgt | SERP1207 | SERP1203 | ACT domain protein; Identified by match to protein family HMM PF01842; Belongs to the UPF0735 family. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...] | 0.868 |
| SERP1207 | yajC | SERP1207 | SERP1202 | ACT domain protein; Identified by match to protein family HMM PF01842; Belongs to the UPF0735 family. | Preprotein translocase, YajC subunit; Identified by match to protein family HMM PF02699; match to protein family HMM TIGR00739. | 0.864 |
| SERP1210 | SERP1207 | SERP1210 | SERP1207 | Conserved hypothetical protein; Identified by similarity to OMNI:SA1701; match to protein family HMM PF04327. | ACT domain protein; Identified by match to protein family HMM PF01842; Belongs to the UPF0735 family. | 0.824 |
| SERP1210 | obg | SERP1210 | SERP1208 | Conserved hypothetical protein; Identified by similarity to OMNI:SA1701; match to protein family HMM PF04327. | GTP-binding protein, GTP1/OBG family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.800 |
| SERP1210 | queA | SERP1210 | SERP1204 | Conserved hypothetical protein; Identified by similarity to OMNI:SA1701; match to protein family HMM PF04327. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.790 |
| SERP1210 | rpmA | SERP1210 | SERP1209 | Conserved hypothetical protein; Identified by similarity to OMNI:SA1701; match to protein family HMM PF04327. | Ribosomal protein L27; Identified by match to protein family HMM PF01016; match to protein family HMM TIGR00062; Belongs to the bacterial ribosomal protein bL27 family. | 0.999 |
| SERP1210 | ruvA | SERP1210 | SERP1206 | Conserved hypothetical protein; Identified by similarity to OMNI:SA1701; match to protein family HMM PF04327. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.795 |
| SERP1210 | ruvB | SERP1210 | SERP1205 | Conserved hypothetical protein; Identified by similarity to OMNI:SA1701; match to protein family HMM PF04327. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.790 |
| SERP1210 | tgt | SERP1210 | SERP1203 | Conserved hypothetical protein; Identified by similarity to OMNI:SA1701; match to protein family HMM PF04327. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...] | 0.780 |
| SERP1210 | yajC | SERP1210 | SERP1202 | Conserved hypothetical protein; Identified by similarity to OMNI:SA1701; match to protein family HMM PF04327. | Preprotein translocase, YajC subunit; Identified by match to protein family HMM PF02699; match to protein family HMM TIGR00739. | 0.775 |
| obg | SERP1207 | SERP1208 | SERP1207 | GTP-binding protein, GTP1/OBG family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | ACT domain protein; Identified by match to protein family HMM PF01842; Belongs to the UPF0735 family. | 0.891 |
| obg | SERP1210 | SERP1208 | SERP1210 | GTP-binding protein, GTP1/OBG family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Conserved hypothetical protein; Identified by similarity to OMNI:SA1701; match to protein family HMM PF04327. | 0.800 |
| obg | queA | SERP1208 | SERP1204 | GTP-binding protein, GTP1/OBG family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.875 |
| obg | rpmA | SERP1208 | SERP1209 | GTP-binding protein, GTP1/OBG family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal protein L27; Identified by match to protein family HMM PF01016; match to protein family HMM TIGR00062; Belongs to the bacterial ribosomal protein bL27 family. | 0.984 |