node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SERP1308 | SERP1310 | SERP1308 | SERP1310 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA1627; match to protein family HMM PF01636. | Dipeptidase family protein; Identified by similarity to GP:2160707; match to protein family HMM PF01546; match to protein family HMM TIGR01887. | 0.767 |
SERP1308 | dat | SERP1308 | SERP1309 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA1627; match to protein family HMM PF01636. | D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essen [...] | 0.771 |
SERP1308 | trmB | SERP1308 | SERP1307 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA1627; match to protein family HMM PF01636. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.883 |
SERP1310 | SERP1308 | SERP1310 | SERP1308 | Dipeptidase family protein; Identified by similarity to GP:2160707; match to protein family HMM PF01546; match to protein family HMM TIGR01887. | Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA1627; match to protein family HMM PF01636. | 0.767 |
SERP1310 | dat | SERP1310 | SERP1309 | Dipeptidase family protein; Identified by similarity to GP:2160707; match to protein family HMM PF01546; match to protein family HMM TIGR01887. | D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essen [...] | 0.901 |
SERP1310 | trmB | SERP1310 | SERP1307 | Dipeptidase family protein; Identified by similarity to GP:2160707; match to protein family HMM PF01546; match to protein family HMM TIGR01887. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.764 |
dat | SERP1308 | SERP1309 | SERP1308 | D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essen [...] | Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SA1627; match to protein family HMM PF01636. | 0.771 |
dat | SERP1310 | SERP1309 | SERP1310 | D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essen [...] | Dipeptidase family protein; Identified by similarity to GP:2160707; match to protein family HMM PF01546; match to protein family HMM TIGR01887. | 0.901 |
dat | trmB | SERP1309 | SERP1307 | D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essen [...] | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.770 |
nusG | purR | SERP0177 | SERP0134 | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | Pur operon repressor; Identified by similarity to EGAD:16043; match to protein family HMM PF00156; match to protein family HMM TIGR01743. | 0.481 |
nusG | rimP | SERP0177 | SERP0832 | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.581 |
nusG | sun | SERP0177 | SERP0783 | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.617 |
nusG | tgt | SERP0177 | SERP1203 | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...] | 0.784 |
nusG | trmB | SERP0177 | SERP1307 | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.772 |
nusG | truA | SERP0177 | SERP1800 | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.798 |
purR | nusG | SERP0134 | SERP0177 | Pur operon repressor; Identified by similarity to EGAD:16043; match to protein family HMM PF00156; match to protein family HMM TIGR01743. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.481 |
purR | tgt | SERP0134 | SERP1203 | Pur operon repressor; Identified by similarity to EGAD:16043; match to protein family HMM PF00156; match to protein family HMM TIGR01743. | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...] | 0.656 |
purR | trmB | SERP0134 | SERP1307 | Pur operon repressor; Identified by similarity to EGAD:16043; match to protein family HMM PF00156; match to protein family HMM TIGR01743. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.652 |
purR | truA | SERP0134 | SERP1800 | Pur operon repressor; Identified by similarity to EGAD:16043; match to protein family HMM PF00156; match to protein family HMM TIGR01743. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.602 |
rimP | nusG | SERP0832 | SERP0177 | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.581 |