STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
agrAAccessory gene regulator protein A; Required for high-level post-exponential phase expression of a series of secreted proteins. (223 aa)    
Predicted Functional Partners:
agrC
Accessory gene regulator protein C; Identified by similarity to GP:2258296; match to protein family HMM PF02518.
 
 
 0.996
agrB
Accessory gene regulator protein B; Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP; Belongs to the AgrB family.
 
  
 0.967
agrD
Accessory gene regulator protein D; Identified by similarity to EGAD:18902.
       0.576
lytS
Sensor histidine kinase LytS; Member of the two-component regulatory system LytR/LytS that probably regulates genes involved in cell wall metabolism.
  
 
 0.546
dltD
dltD protein; Identified by match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918.
  
     0.444
SERP2263
N-acetylmuramoyl-L-alanine amidase domain protein; Identified by match to protein family HMM PF01832; match to protein family HMM PF05257.
  
   
 0.440
srtA
Sortase; Identified by similarity to GP:5726436; match to protein family HMM PF04203; match to protein family HMM TIGR01076.
 
   
 0.426
SERP1997
Identified by match to protein family HMM PF01226.
  
  
 0.403
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.