STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERP1513Truncated ribonucleoside-diphosphate reductase 2, alpha subunit; Contains a 384 residue intein; identified by match to protein family HMM PF00317; match to protein family HMM PF02867; match to protein family HMM TIGR01443; match to protein family HMM TIGR01445; may be nonfunctional due to interuption. (969 aa)    
Predicted Functional Partners:
nrdF-2
Ribonucleoside-diphosphate reductase 2, beta subunit; Identified by similarity to EGAD:37758; match to protein family HMM PF00268.
 
 0.998
nrdF-1
Ribonucleoside-diphosphate reductase 2, beta subunit; Identified by similarity to EGAD:37758; match to protein family HMM PF00268.
 
 0.997
nrdI-2
nrdI protein; Identified by match to protein family HMM PF02555; match to protein family HMM TIGR00333; Belongs to the NrdI family.
 
  
 0.977
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.943
nrdI-1
nrdI protein; Probably involved in ribonucleotide reductase function.
 
  
 0.922
nrdE
Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
0.915
cmk
Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017.
  
 
 0.914
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.914
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.908
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.908
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.