Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SERP1586Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583. (130 aa)    
Predicted Functional Partners:
aacA
6'-aminoglycoside N-acetyltransferase/2''-aminoglycoside phosphotransferase; Involved in resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region. The C-terminal region is a kinase that phosphorylates several 4,6-disubstituted aminoglycosides.
 
 
 0.956
SERP2264
Cell wall surface anchor family protein.
  
     0.662
SERP2063
Esterase, putative; Identified by similarity to SP:P22862.
  
    0.637
SERP0093
Conserved hypothetical protein; Identified by similarity to EGAD:162731.
  
     0.632
agrB
Accessory gene regulator protein B; Essential for the production of a quorum sensing system signal molecule, the autoinducing peptide (AIP). This quorum sensing system is responsible for the regulation of the expression of virulence factor genes. Involved in the proteolytic processing of AgrD, the precursor of AIP; Belongs to the AgrB family.
  
     0.622
SERP0331
Conserved hypothetical protein; Identified by similarity to OMNI:SA0735.
  
     0.618
SERP1587
IS256-like transposase; Identified by similarity to EGAD:22488; match to protein family HMM PF00872.
       0.603
sdrH
sdrH protein; Identified by similarity to GP:8101009.
  
     0.597
SERP1588
IS431mec-like transposase; Identified by similarity to OMNI:SA0028; may be nonfunctional due to interuption.
 
     0.522
SERP2010
Conserved hypothetical protein; Identified by similarity to OMNI:SA1738.
  
     0.508
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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