node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SERP0969 | SERP1691 | SERP0969 | SERP1691 | Alanine racemase family protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Cell division protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | 0.430 |
SERP0969 | alr | SERP0969 | SERP1683 | Alanine racemase family protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.927 |
SERP0969 | dat | SERP0969 | SERP1309 | Alanine racemase family protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essen [...] | 0.920 |
SERP0969 | ddl | SERP0969 | SERP1690 | Alanine racemase family protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.944 |
SERP0969 | dltA | SERP0969 | SERP0518 | Alanine racemase family protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...] | 0.912 |
SERP0969 | dltC | SERP0969 | SERP0520 | Alanine racemase family protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.902 |
SERP0969 | murD | SERP0969 | SERP0748 | Alanine racemase family protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.468 |
SERP1691 | SERP0969 | SERP1691 | SERP0969 | Cell division protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | Alanine racemase family protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.430 |
SERP1691 | alr | SERP1691 | SERP1683 | Cell division protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.604 |
SERP1691 | ddl | SERP1691 | SERP1690 | Cell division protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.880 |
SERP1691 | murB | SERP1691 | SERP0405 | Cell division protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.483 |
SERP1691 | murC | SERP1691 | SERP1300 | Cell division protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.862 |
SERP1691 | murD | SERP1691 | SERP0748 | Cell division protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.867 |
SERP1691 | murF | SERP1691 | SERP1689 | Cell division protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.944 |
alr | SERP0969 | SERP1683 | SERP0969 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Alanine racemase family protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.927 |
alr | SERP1691 | SERP1683 | SERP1691 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Cell division protein, FtsW/RodA/SpoVE family; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | 0.604 |
alr | dat | SERP1683 | SERP1309 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essen [...] | 0.935 |
alr | ddl | SERP1683 | SERP1690 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.975 |
alr | dltA | SERP1683 | SERP0518 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...] | 0.912 |
alr | dltC | SERP1683 | SERP0520 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.902 |