Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lacFPTS system, lactose-specific IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LacEF PTS system is involved in lactose transport. (104 aa)    
Predicted Functional Partners:
lacE
PTS system, lactose-specific IIBC components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LacEF PTS system is involved in lactose transport.
 
 0.999
lacG
6-phospho-beta-galactosidase; Identified by similarity to EGAD:22248; match to protein family HMM PF00232; match to protein family HMM TIGR01233; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.998
lacC
Tagatose-6-phosphate kinase; Identified by similarity to EGAD:6991; match to protein family HMM PF00294; match to protein family HMM TIGR01231; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.988
lacD
Tagatose 1,6-diphosphate aldolase; Identified by similarity to EGAD:9829; match to protein family HMM PF04274; match to protein family HMM TIGR01232; Belongs to the aldolase LacD family.
 
  
 0.961
ptsH
Phosphocarrier protein HPr; Identified by similarity to EGAD:6430; match to protein family HMM PF00381; match to protein family HMM TIGR01003.
   
 0.950
lacB
Galactose-6-phosphate isomerase, LacB subunit; Identified by similarity to EGAD:16117; match to protein family HMM PF02502; match to protein family HMM TIGR00689.
 
  
 0.941
lacA
Galactose-6-phosphate isomerase, LacA subunit; Identified by similarity to EGAD:13018; match to protein family HMM PF02502; match to protein family HMM TIGR00689.
 
  
 0.930
SERP2259
Transcriptional antiterminator, BglG family; Identified by match to protein family HMM PF00359; match to protein family HMM PF00874.
 
  
 0.831
galM
Aldose 1-epimerase; Identified by similarity to EGAD:7416; match to protein family HMM PF01263.
  
  
 0.774
SERP1898
Conserved hypothetical protein; Identified by similarity to GP:14245957.
 
     0.715
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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