STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureFUrease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (229 aa)    
Predicted Functional Partners:
ureC
Urease, alpha subunit; Identified by similarity to EGAD:98226; match to protein family HMM PF00449; match to protein family HMM PF01979; match to protein family HMM TIGR01792; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
 
 0.999
ureE
Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.999
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.999
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.999
ureA
Urease, gamma subunit; Identified by match to protein family HMM PF00547; match to protein family HMM TIGR00193; Belongs to the urease gamma subunit family.
 
 
 0.998
ureB
Urease, beta subunit; Identified by match to protein family HMM PF00699; match to protein family HMM TIGR00192; Belongs to the urease beta subunit family.
 
 
 0.997
SERP1868
Transporter, putative; Identified by match to protein family HMM PF03253.
 
  
 0.885
ipdC
Indole-3-pyruvate decarboxylase; Identified by similarity to EGAD:20234; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776.
      
 0.688
hutG
Formiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
  
  
 0.631
fdaB
Fructose-bisphosphate aldolase, class I; Identified by similarity to SP:Q07159; match to protein family HMM PF00274; Belongs to the class I fructose-bisphosphate aldolase family.
      
 0.605
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.