Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SERP1900PTS system, IIBC components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. (474 aa)    
Predicted Functional Partners:
crr
PTS system, IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II complex composed of PtsG and Crr is involved in glucose transport.
 
 0.984
cscA
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
 
 0.975
SERP1968
PTS system, sucrose-specific IIBC components; Identified by similarity to EGAD:18969; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826.
 
 
0.944
SERP1898
Conserved hypothetical protein; Identified by similarity to GP:14245957.
 
     0.943
ptsG
PTS system, IIABC components; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.
 
0.942
ptsH
Phosphocarrier protein HPr; Identified by similarity to EGAD:6430; match to protein family HMM PF00381; match to protein family HMM TIGR01003.
  
 
 0.938
murQ
Glucokinase regulator-related protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
 
  
 0.932
SERP1901
Phosphosugar-binding transcriptional regulator, RpiR family; Identified by match to protein family HMM PF01380; match to protein family HMM PF01418.
 
  
 0.912
SERP2260
PTS system, fructose-specific IIABC components; Identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427.
 
  
 0.894
SERP2259
Transcriptional antiterminator, BglG family; Identified by match to protein family HMM PF00359; match to protein family HMM PF00874.
 
 
 0.858
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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