STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fni-2Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (349 aa)    
Predicted Functional Partners:
mvaD
Mevalonate diphosphate decarboxylase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01240.
 
  
 0.980
SERP0240
Phosphomevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR01220.
  
 0.939
ispA
Geranyltranstransferase; Identified by similarity to SP:Q08291; match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
  
 
 0.923
SERP2121
hydroxymethylglutaryl-CoA reductase, degradative; Identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; Belongs to the HMG-CoA reductase family.
   
 0.868
mvk
Mevalonate kinase; Identified by match to protein family HMM PF00288; match to protein family HMM TIGR00549.
 
  
 0.833
SERP1957
L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
  
  
 0.812
SERP1939
Conserved hypothetical protein; Identified by similarity to OMNI:SA2343.
       0.796
SERP2122
hydroxymethylglutaryl-CoA synthase; Identified by match to protein family HMM PF01154; match to protein family HMM TIGR01835.
 
  
 0.783
corA
Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
       0.690
SERP2381
NADH:flavin oxidoreductase/fumarate reductase, flavoprotein subunit, putative; Identified by similarity to EGAD:16535; match to protein family HMM PF00724; match to protein family HMM PF00890; match to protein family HMM PF04205; match to protein family HMM TIGR01813.
  
  
 0.629
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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