| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SERP1950 | tcaR | SERP1950 | SERP1949 | Membrane protein, putative; Identified by match to protein family HMM PF02698. | Transcriptional regulator TcaR; Identified by similarity to OMNI:SA2353; match to protein family HMM PF01047. | 0.531 |
| icaA | icaR | SERP2293 | SERP2292 | Intercellular adhesion protein A; N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity. | Intercellular adhesion regulator; Represses transcription of the icaADBC operon necessary for biofilm production. | 0.957 |
| icaA | rsbU | SERP2293 | SERP1680 | Intercellular adhesion protein A; N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity. | Sigma factor B regulator protein; Identified by similarity to GP:1729794. | 0.783 |
| icaA | sarA | SERP2293 | SERP0274 | Intercellular adhesion protein A; N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity. | Staphylococcal accessory regulator A; Identified by similarity to EGAD:42500; match to protein family HMM TIGR01889. | 0.833 |
| icaA | sarX | SERP2293 | SERP0321 | Intercellular adhesion protein A; N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity. | Staphylococcal accessory regulator family; Identified by match to protein family HMM TIGR01889. | 0.441 |
| icaA | tcaR | SERP2293 | SERP1949 | Intercellular adhesion protein A; N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity. | Transcriptional regulator TcaR; Identified by similarity to OMNI:SA2353; match to protein family HMM PF01047. | 0.437 |
| icaR | icaA | SERP2292 | SERP2293 | Intercellular adhesion regulator; Represses transcription of the icaADBC operon necessary for biofilm production. | Intercellular adhesion protein A; N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity. | 0.957 |
| icaR | rpoF | SERP2292 | SERP1677 | Intercellular adhesion regulator; Represses transcription of the icaADBC operon necessary for biofilm production. | RNA polymerase sigma-37 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.469 |
| icaR | rsbU | SERP2292 | SERP1680 | Intercellular adhesion regulator; Represses transcription of the icaADBC operon necessary for biofilm production. | Sigma factor B regulator protein; Identified by similarity to GP:1729794. | 0.652 |
| icaR | sarA | SERP2292 | SERP0274 | Intercellular adhesion regulator; Represses transcription of the icaADBC operon necessary for biofilm production. | Staphylococcal accessory regulator A; Identified by similarity to EGAD:42500; match to protein family HMM TIGR01889. | 0.849 |
| icaR | sarX | SERP2292 | SERP0321 | Intercellular adhesion regulator; Represses transcription of the icaADBC operon necessary for biofilm production. | Staphylococcal accessory regulator family; Identified by match to protein family HMM TIGR01889. | 0.613 |
| icaR | tcaR | SERP2292 | SERP1949 | Intercellular adhesion regulator; Represses transcription of the icaADBC operon necessary for biofilm production. | Transcriptional regulator TcaR; Identified by similarity to OMNI:SA2353; match to protein family HMM PF01047. | 0.755 |
| rpoF | icaR | SERP1677 | SERP2292 | RNA polymerase sigma-37 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Intercellular adhesion regulator; Represses transcription of the icaADBC operon necessary for biofilm production. | 0.469 |
| rpoF | rsbU | SERP1677 | SERP1680 | RNA polymerase sigma-37 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sigma factor B regulator protein; Identified by similarity to GP:1729794. | 0.978 |
| rpoF | sarA | SERP1677 | SERP0274 | RNA polymerase sigma-37 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Staphylococcal accessory regulator A; Identified by similarity to EGAD:42500; match to protein family HMM TIGR01889. | 0.498 |
| rpoF | tcaR | SERP1677 | SERP1949 | RNA polymerase sigma-37 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Transcriptional regulator TcaR; Identified by similarity to OMNI:SA2353; match to protein family HMM PF01047. | 0.416 |
| rsbU | icaA | SERP1680 | SERP2293 | Sigma factor B regulator protein; Identified by similarity to GP:1729794. | Intercellular adhesion protein A; N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity. | 0.783 |
| rsbU | icaR | SERP1680 | SERP2292 | Sigma factor B regulator protein; Identified by similarity to GP:1729794. | Intercellular adhesion regulator; Represses transcription of the icaADBC operon necessary for biofilm production. | 0.652 |
| rsbU | rpoF | SERP1680 | SERP1677 | Sigma factor B regulator protein; Identified by similarity to GP:1729794. | RNA polymerase sigma-37 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.978 |
| rsbU | sarA | SERP1680 | SERP0274 | Sigma factor B regulator protein; Identified by similarity to GP:1729794. | Staphylococcal accessory regulator A; Identified by similarity to EGAD:42500; match to protein family HMM TIGR01889. | 0.769 |