Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SERP1978Identified by match to protein family HMM PF00881. (209 aa)    
Predicted Functional Partners:
sarZ
Transcriptional regulator, MarR family; Identified by match to protein family HMM PF01047.
  
    0.727
SERP0887
ABC transporter, permease protein.
  
  
 0.567
SERP1977
Conserved hypothetical protein.
       0.533
birA
birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.523
tadA
Cytidine/deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
    0.499
SERP2068
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01HSA00233; match to protein family HMM PF02619; match to protein family HMM PF03992.
 
    0.478
SERP2377
Conserved domain protein.
  
    0.476
nfrA
NAD(P)H-flavin oxidoreductase, putative; Reduces FMN, organic nitro compounds and disulfide DTNB. Involved in maintenance of the cellular redox state and the disulfide stress response (By similarity); Belongs to the flavin oxidoreductase frp family.
  
   
 0.446
SERP0035
Homocysteine S-methyltransferase/5-methyltetrahydrofolate--homocysteine methyltransferase, putative; Identified by match to protein family HMM PF02219; match to protein family HMM PF02574.
 
  
 0.419
vraA
Long chain fatty acid CoA ligase, putative; Identified by match to protein family HMM PF00501; Belongs to the ATP-dependent AMP-binding enzyme family.
   
   0.407
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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