| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SERP0888 | nreB | SERP0888 | SERP1982 | Sensor histidine kinase, putative; Identified by match to protein family HMM PF02518. | Sensor histidine kinase, putative; Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT (By similarity). | 0.773 |
| SERP0888 | nreC | SERP0888 | SERP1981 | Sensor histidine kinase, putative; Identified by match to protein family HMM PF02518. | Transcriptional regulatory protein DegU, putative; Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity). | 0.916 |
| SERP0888 | vraS | SERP0888 | SERP1423 | Sensor histidine kinase, putative; Identified by match to protein family HMM PF02518. | Sensor histidine kinase VraS; Member of the two-component regulatory system VraS/VraR involved in the control of the cell wall peptidoglycan biosynthesis. Probably activates VraR by phosphorylation (By similarity). | 0.772 |
| SERP1385 | nreC | SERP1385 | SERP1981 | Sensor histidine kinase; Identified by match to protein family HMM PF02518. | Transcriptional regulatory protein DegU, putative; Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity). | 0.946 |
| SERP1983 | narG | SERP1983 | SERP1987 | Conserved hypothetical protein. | Respiratory nitrate reductase, alpha subunit; Identified by similarity to EGAD:30702; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.836 |
| SERP1983 | narH | SERP1983 | SERP1986 | Conserved hypothetical protein. | Respiratory nitrate reductase, beta subunit; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01660. | 0.800 |
| SERP1983 | narI | SERP1983 | SERP1984 | Conserved hypothetical protein. | Respiratory nitrate reductase, gamma subunit; Identified by similarity to EGAD:30704; match to protein family HMM PF02665; match to protein family HMM TIGR00351. | 0.810 |
| SERP1983 | narJ | SERP1983 | SERP1985 | Conserved hypothetical protein. | Respiratory nitrate reductase, delta subunit; Identified by similarity to EGAD:30705; match to protein family HMM PF02613; match to protein family HMM TIGR00684. | 0.934 |
| SERP1983 | narT | SERP1983 | SERP1980 | Conserved hypothetical protein. | Nitrite extrusion protein; Probably required for nitrate uptake under anoxic conditions. Also possibly involved in excretion of nitrite produced by the dissimilatory reduction of nitrate (By similarity). | 0.812 |
| SERP1983 | nreB | SERP1983 | SERP1982 | Conserved hypothetical protein. | Sensor histidine kinase, putative; Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT (By similarity). | 0.966 |
| SERP1983 | nreC | SERP1983 | SERP1981 | Conserved hypothetical protein. | Transcriptional regulatory protein DegU, putative; Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity). | 0.892 |
| narG | SERP1983 | SERP1987 | SERP1983 | Respiratory nitrate reductase, alpha subunit; Identified by similarity to EGAD:30702; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Conserved hypothetical protein. | 0.836 |
| narG | narH | SERP1987 | SERP1986 | Respiratory nitrate reductase, alpha subunit; Identified by similarity to EGAD:30702; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Respiratory nitrate reductase, beta subunit; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01660. | 0.999 |
| narG | narI | SERP1987 | SERP1984 | Respiratory nitrate reductase, alpha subunit; Identified by similarity to EGAD:30702; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Respiratory nitrate reductase, gamma subunit; Identified by similarity to EGAD:30704; match to protein family HMM PF02665; match to protein family HMM TIGR00351. | 0.999 |
| narG | narJ | SERP1987 | SERP1985 | Respiratory nitrate reductase, alpha subunit; Identified by similarity to EGAD:30702; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Respiratory nitrate reductase, delta subunit; Identified by similarity to EGAD:30705; match to protein family HMM PF02613; match to protein family HMM TIGR00684. | 0.999 |
| narG | narT | SERP1987 | SERP1980 | Respiratory nitrate reductase, alpha subunit; Identified by similarity to EGAD:30702; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Nitrite extrusion protein; Probably required for nitrate uptake under anoxic conditions. Also possibly involved in excretion of nitrite produced by the dissimilatory reduction of nitrate (By similarity). | 0.952 |
| narG | nreB | SERP1987 | SERP1982 | Respiratory nitrate reductase, alpha subunit; Identified by similarity to EGAD:30702; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Sensor histidine kinase, putative; Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT (By similarity). | 0.835 |
| narG | nreC | SERP1987 | SERP1981 | Respiratory nitrate reductase, alpha subunit; Identified by similarity to EGAD:30702; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Transcriptional regulatory protein DegU, putative; Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity). | 0.760 |
| narH | SERP1983 | SERP1986 | SERP1983 | Respiratory nitrate reductase, beta subunit; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01660. | Conserved hypothetical protein. | 0.800 |
| narH | narG | SERP1986 | SERP1987 | Respiratory nitrate reductase, beta subunit; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR01660. | Respiratory nitrate reductase, alpha subunit; Identified by similarity to EGAD:30702; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.999 |
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