Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SERP1997Identified by match to protein family HMM PF01226. (273 aa)    
Predicted Functional Partners:
nirB
Nitrite reductase [NAD(P)H], large subunit; Identified by similarity to EGAD:30822; match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.566
SERP0389
Alcohol dehydrogenase, iron-containing; Identified by similarity to SP:P17547; match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.530
nirD
Nitrite reductase [NAD(P)H], small subunit; Identified by similarity to EGAD:30823; match to protein family HMM PF00355.
  
  
 0.480
SERP1998
Conserved hypothetical protein; Identified by similarity to OMNI:SA2402; match to protein family HMM PF05146.
       0.429
pflB
Formate acetyltransferase; Identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
  
  
 0.421
SERP0325
Flavohemoprotein, putative; Identified by match to protein family HMM PF00042; match to protein family HMM PF00970; Belongs to the globin family.
  
  
 0.415
agrA
Accessory gene regulator protein A; Required for high-level post-exponential phase expression of a series of secreted proteins.
  
  
 0.409
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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