Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
budAAlpha-acetolactate decarboxylase; Identified by similarity to EGAD:17067; match to protein family HMM PF03306; match to protein family HMM TIGR01252; Belongs to the alpha-acetolactate decarboxylase family. (234 aa)    
Predicted Functional Partners:
budB
Acetolactate synthase, catabolic; Identified by similarity to EGAD:14077; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family.
 
 
 0.996
ilvB
Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P37251; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118.
  
 
 0.963
SERP2032
Sorbitol dehydrogenase, putative; Identified by match to protein family HMM PF00107.
     
 0.937
SERP1667
Acetolactate synthase, small subunit, truncation; Identified by similarity to EGAD:12389; match to protein family HMM PF01842.
     
 0.910
SERP2257
Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by similarity to GP:5777659; match to protein family HMM PF00106; match to protein family HMM PF00678.
     
 0.905
butA
Oxidoreductase, short-chain dehydrogenase/reductase family; Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.905
SERP2115
Pyruvate oxidase; Identified by similarity to EGAD:10763; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family.
 
  
 0.738
pflB
Formate acetyltransferase; Identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
      
 0.587
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
     
 0.573
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
      
 0.507
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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