| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SERP0856 | SERP0857 | SERP0856 | SERP0857 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to EGAD:20923; match to protein family HMM PF02775. | 0.999 |
| SERP0856 | SERP1667 | SERP0856 | SERP1667 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | Acetolactate synthase, small subunit, truncation; Identified by similarity to EGAD:12389; match to protein family HMM PF01842. | 0.924 |
| SERP0856 | budB | SERP0856 | SERP2155 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | Acetolactate synthase, catabolic; Identified by similarity to EGAD:14077; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.940 |
| SERP0856 | ilvA | SERP0856 | SERP1673 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). | 0.448 |
| SERP0856 | ilvB | SERP0856 | SERP1666 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P37251; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. | 0.940 |
| SERP0856 | ilvC | SERP0856 | SERP1668 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.434 |
| SERP0856 | ldh | SERP0856 | SERP2156 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.967 |
| SERP0856 | pflB | SERP0856 | SERP2366 | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | Formate acetyltransferase; Identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily. | 0.942 |
| SERP0857 | SERP0856 | SERP0857 | SERP0856 | Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to EGAD:20923; match to protein family HMM PF02775. | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | 0.999 |
| SERP0857 | SERP1667 | SERP0857 | SERP1667 | Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to EGAD:20923; match to protein family HMM PF02775. | Acetolactate synthase, small subunit, truncation; Identified by similarity to EGAD:12389; match to protein family HMM PF01842. | 0.904 |
| SERP0857 | budB | SERP0857 | SERP2155 | Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to EGAD:20923; match to protein family HMM PF02775. | Acetolactate synthase, catabolic; Identified by similarity to EGAD:14077; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.912 |
| SERP0857 | ilvB | SERP0857 | SERP1666 | Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to EGAD:20923; match to protein family HMM PF02775. | Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P37251; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. | 0.912 |
| SERP0857 | ldh | SERP0857 | SERP2156 | Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to EGAD:20923; match to protein family HMM PF02775. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.933 |
| SERP0857 | pflB | SERP0857 | SERP2366 | Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to EGAD:20923; match to protein family HMM PF02775. | Formate acetyltransferase; Identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily. | 0.924 |
| SERP1667 | SERP0856 | SERP1667 | SERP0856 | Acetolactate synthase, small subunit, truncation; Identified by similarity to EGAD:12389; match to protein family HMM PF01842. | Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855. | 0.924 |
| SERP1667 | SERP0857 | SERP1667 | SERP0857 | Acetolactate synthase, small subunit, truncation; Identified by similarity to EGAD:12389; match to protein family HMM PF01842. | Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to EGAD:20923; match to protein family HMM PF02775. | 0.904 |
| SERP1667 | budA | SERP1667 | SERP2154 | Acetolactate synthase, small subunit, truncation; Identified by similarity to EGAD:12389; match to protein family HMM PF01842. | Alpha-acetolactate decarboxylase; Identified by similarity to EGAD:17067; match to protein family HMM PF03306; match to protein family HMM TIGR01252; Belongs to the alpha-acetolactate decarboxylase family. | 0.914 |
| SERP1667 | budB | SERP1667 | SERP2155 | Acetolactate synthase, small subunit, truncation; Identified by similarity to EGAD:12389; match to protein family HMM PF01842. | Acetolactate synthase, catabolic; Identified by similarity to EGAD:14077; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. | 0.983 |
| SERP1667 | ilvA | SERP1667 | SERP1673 | Acetolactate synthase, small subunit, truncation; Identified by similarity to EGAD:12389; match to protein family HMM PF01842. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). | 0.991 |
| SERP1667 | ilvB | SERP1667 | SERP1666 | Acetolactate synthase, small subunit, truncation; Identified by similarity to EGAD:12389; match to protein family HMM PF01842. | Acetolactate synthase, large subunit, biosynthetic type; Identified by similarity to SP:P37251; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118. | 0.997 |