Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
SERP2172acetyl-CoA synthetase, putative; Identified by similarity to EGAD:18603; match to protein family HMM PF00501. (531 aa)    
Predicted Functional Partners:
SERP0856
Pyruvate ferredoxin oxidoreductase, alpha subunit; Identified by similarity to EGAD:21889; match to protein family HMM PF01558; match to protein family HMM PF01855.
  
 
 0.967
gltA
Citrate synthase; Identified by similarity to EGAD:21870; match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.
  
 0.948
SERP2381
NADH:flavin oxidoreductase/fumarate reductase, flavoprotein subunit, putative; Identified by similarity to EGAD:16535; match to protein family HMM PF00724; match to protein family HMM PF00890; match to protein family HMM PF04205; match to protein family HMM TIGR01813.
  
 
 0.943
SERP0389
Alcohol dehydrogenase, iron-containing; Identified by similarity to SP:P17547; match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.942
SERP0032
acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.933
vraB
acetyl-CoA acetyltransferase, putative; Identified by match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.933
pta
Phosphate acetyltransferase; Identified by similarity to SP:P39646; match to protein family HMM PF01515; match to protein family HMM TIGR00651.
  
 
 0.931
accC
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.930
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.929
SERP0857
Pyruvate ferredoxin oxidoreductase, beta subunit; Identified by similarity to EGAD:20923; match to protein family HMM PF02775.
  
 
 0.922
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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