STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysJSulfite reductase (NADPH) flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (614 aa)    
Predicted Functional Partners:
cysI
Sulfite reductase (NADPH) hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 0.999
cysH
Phosophoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
 
 0.996
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
 
 0.988
SERP0037
Identified by match to protein family HMM PF01053.
  
 0.978
cysK
Cysteine synthase; Identified by similarity to SP:P37887; match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.976
sat
Sulfate adenylyltransferase; Identified by match to protein family HMM PF01747; match to protein family HMM TIGR00339; Belongs to the sulfate adenylyltransferase family.
  
  
 0.972
SERP0035
Homocysteine S-methyltransferase/5-methyltetrahydrofolate--homocysteine methyltransferase, putative; Identified by match to protein family HMM PF02219; match to protein family HMM PF02574.
 
 0.949
SERP0095
Identified by match to protein family HMM PF01053.
  
 0.916
SERP1451
Nitric-oxide synthase, oxygenase subunit; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
 
     0.913
SERP2188
Siroheme synthase, putative; Identified by match to protein family HMM TIGR01470.
 
  
 0.889
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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