STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arcRTranscriptional regulator, Crp/Fnr family; Positively regulates the expression of the arcABDCR operon under anaerobic conditions, thus playing an essential role in arginine catabolism. May also control the expression of genes encoding proteins which are involved in anaerobic metabolism. Can bind cyclic AMP (By similarity). (228 aa)    
Predicted Functional Partners:
arcD
Arginine/ornithine antiporter; Identified by similarity to EGAD:21315; match to protein family HMM PF00324; match to protein family HMM TIGR00905.
 
  
 0.882
SERP0372
6-pyruvoyl tetrahydrobiopterin synthase, putative; Identified by match to protein family HMM PF01242.
    
  0.835
yvcD
yvcD protein; Identified by similarity to GP:5690062; match to protein family HMM PF00515.
 
 
 0.806
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.800
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   0.773
SERP1184
TPR domain protein; Identified by similarity to OMNI:SA1675; match to protein family HMM PF00515.
   
 0.745
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.743
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.709
arcC
Carbamate kinase; Identified by similarity to SP:P35836; match to protein family HMM PF00696; match to protein family HMM TIGR00746.
     
 0.687
glpF
Glycerol uptake facilitator protein; Identified by similarity to EGAD:21817; match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 0.686
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.